DEPARTMENT OF BIOCHEMISTRY

Department of Biochemistry started from 2014 in ACSR Government Medical College, as Teaching, practical and investigations department. The full time teaching faculty educates and train students of various courses undergraduate MBBS & Nursing teaching as per NMC – CBME and YSRUHS guidelines. The clinical laboratory was also present in GGH, SPSR Nellore where it was expanded by acquiring state of art equipment and increasing the number and types of investigations performed. Since its inception, the department has flourished focusing on three core aspects: Teaching, Patient care services and Research. Currently, the tests are performed using fully automated techniques and latest methods. It present we are performing IP, OP, MCH and Aarogya sree samples around 500 samples per day investigations such as like Glucose, RFT, LFT, Lipids, Thyroids, ABG analysis and electrolytes. The central biochemistry laboratory runs 24 hours a day and all 365 days to provide emergency investigation facilities. We also followed internal and external quality control program for patient care services. Faculty and students of Biochemistry have regularly been receiving awards for their research work and publications in various National and International. Weekly patient care review and quality audit meetings are held to continuously improve upon patient care service.

Dr. KONDETI MADHAVIi MD
Professor & HOD

HOD OF BIOCHEMISTRY, Dr. Kondeti Madhavi MBBS, M.D

  • MBBS at SV Medical College, 1992 Siddhartha Medical College,
  • MD 1999 at SV Medical College, SVMC
  • 1993-95 Residency in Endocrinology and Metabolism, SVIMS,
  • 1992-93 Volunteer in Riverside Methodist Hospital, Columbus, Ohio,
  • Academic Council member of Dr YSRUHS library
  • Board of studies member at Padmavati Medical College for women,
  • Ethical committee member of SPG COLLEGE OF
  • MDRU Nodal officer 2018 to 2022in SVMC,
  • Board of studies member of Mahila University,
  • Academic member of RSSDI,
  • Cultural committee member of Dr NTR UHS
  • Best Teacher award 2018
  • Best Teacher award by IMA
  • Best Doctor Award of Chittoor District,
  • Best Doctor Award in Covid 19 – pandemic in
  • Workshop in Molecular Biology under DHR in MDRU, SVMC, Tirupati
  • Scientific committee convener and coordinator, SVMC, Tirupati from 2018-
  • Convener and coordinator Research Advisory Committee, MDRU and MRHRU, Tirupati from 2018-2022.
  • ICMR-DHR workshop on Strengthening of Clinical Laboratory Practices in Rural Government Hospital of SPSR Nellore, District. DHR-ICMR Workshop approved on 01.10.2023 Date of Submission: 28.06.2023, Date of Post-posed to : 18.11.2023 to 20.11.2023.

ACTIVITIES CARRIED OUT BY THE DEPARTMENT

  1. Provide a unique opportunity for students to undertake core professional and research skill education.
  2. Continuous trainings are given to laboratory technical staff regarding Laboratory information system (LIS), automation, quality control and able to understand pre-analytical, analytical and post analytical procedures.
  3. Student’s participation in all UG activates through Seminars, Group discussions and self directed learning etc is mandatory and provides training oral communication skills.
  4. ICMR workshops and UG STS projects are continuous going on in the department.

FACULTY LIST

Sl.No. Name of the Faculty Designation
1
Dr. Kondati Madhavi MBBS. M.D
Professor and HOD
2
Dr. P. Laxmi MBBS. M.D
Associate Professor
3
Dr. M. Prasanth MBBS. M.D
Assistant Professor
4
Dr. G. Sarvari M. Sc Ph. D
Assistant Professor
5
Dr. P. Pullaiah M. Sc Ph. D
Assistant Professor
6
Dr. M. Keethithej MBBS. M.D
Assistant Professor
7
Dr. Y. Rama Krishna Reddy M. Sc Ph. D
Assistant Professor

LIST OF THE PUBLICATIONS

 

S.

No

Name of the Faculty with Designation

Title

Journal     Name                 with publication date

Index

1

Dr. Kondeti Madhavi Professor & HOD

Member of the Editorial Board

Borneo                  Epidemiology Journal UMS (Universiti

Malaysia Sabah)

 

Cost of Surgical Care at Public Sector District Hospitals in India: Implications for  Universal  Health  Coverage  and

Publicly Financed Health Insurance Schemes.

PharmacoEconomics Open 6, 745–756 (2022).

https://doi.org/10.1007/s4 1669-022-00342-6.

Yes

Using Cost Evidence for Price Setting: Experience from a Large National Public Insurance Scheme of India

The Lancet (4/17/2020). Available                                    at

SSRN: https://ssrn.com/a

bstract=3582739

Yes

Measure of serum MDA, GST and Vit C in women with cervical carcinoma.

Ijar. 2021;11: 06. ISSN No 2249 – 555X | DOI :

10.36106/ijar.

Yes

Biomarkers  of  Oxidative                                          Stress  and

Inflammation       in                           Patients                           with Rheumatoid Arthritis

semantic   scholar.   2018

Corpus ID: 221989519

Yes

A Comparative Study of Lipid Profile and Atherogenic  Index  of  Plasma  among

Women with Rheumatoid Arthritis and without Rheumatoid Arthritis.

JMSCR. 2018;06(08):452-8.`

Yes

Phytochemicals and Biogenic Metallic Nanoparticles as Anticancer Agents.

Oxidative Medicine and Cellular Longevity. 2016,

Article ID 3685671, 15.http://dx.doi.org/10.11 55/2016/3685671.

Yes

Correlation between serum Magnesium levels and HbA1C in Type 2 Diabetes

Mellitus

BEJ. 2020;1(2) : 136 – 44.

Yes

 

3

Dr.        P.         Laxmi Associate Professsor

Correlation  of  Serum  uric  acid  with

Glycated Hemoglobin and fasting blood Sugar among Type-II Diabetes mellitus

Clin                         Biochem 2020:10(1):1-6

Yes

Study of Serum Calcium, Creatinineand

Uric acid in Hypothyroid Patient

Int    J     of    Adv    Res.

2022;10(6);1-6

Yes

Association of serum uric acid with atherogenic  index  of  plasma And fasting blood sugar in metabolic syndrome                           among                           diabetic

And non diabetics

Int   J    of    Scient        Res 2022;7(11):1-2

Yes

The Study of Biochemical Abnormalities and      its                  Outcome  in

Neonatal Seizures

Int Jof Pharm and Clin Res 2023;15(4);1529-34

Yes

5

Dr.      M.           Prasanth Assistant Professor

Study of Contrast-induced Oxidative Stress in Nondiabetic Patients Undergoing Coronary Angiography

Saudi    J     Kidney             Dis Transpl 2019;30(1):45-52

© 2019 Saudi Center for

Organ Transplantation

Yes

Drug-interference in clinical chemistry analyses:

pseudohypertriglyceridaemia

JCSR.         2014;3:153-4. DOI:

http://dx.doi.org/10.1538 0/2277-

5706.JCSR.13.045

Yes

synthesis and characterisation of Novel phophorylated derivaties of Zidovudine: Anti cancer activity against human breast

cancer cell lines (MCF 7)

chemistry, biology 2015 Corpus id : 31297526

Yes

6

Dr.          G.               Sarvari Assistant Professor

Association of single nucleotide polymorphisms of adiponection and leptin genes with breast cancer.

Molecular                           Biology Reports. 2019 Doi. 10.1007/s11033-019-

05070-5.

Yes

Breast cancer diagnosis – role of biomarkers.

J       Clin       Sci             Res 2017;6:225-36.        DOI:

http://dx.doi.org/10.1538 0/2277-5706.

JCSR.17.08.005.

Yes

Asymmetric dimethyl arginine levels in patients with diabetic nephropathy.

J       Clin       Sci             Res 2016;5:259-61.        DOI:

http://dx.doi.org/10.1538 0/                              2277-

5706.JCSR.16.05.001.

Yes

Assessment of cardiovascular risk in patients with chronic kidney disease –A study from a tertiary care centre in south

India.

Journal of Indian College of     Cardiology        2018;

8:195–199.

Yes

Molecular biomarkers NOTCH1, CD44, BMI1, and TP53 in oral squamous cell

carcinoma

Bioinformation       19(5):

623-627 (2023)

Yes

7

Dr.       P.            Pullaiah

Impact of COVID-19 on Liver Enzymes: A Retrospective Study.

National      Journal      of

Laboratory                   Medicine. 2022            Apr,    Vol-11(2):

Yes

 

 

Assistant Professor

 

BO10-BO15.

 

Attenuation of Oxidative Stress, Interleukin-6, HighSensitivity C-Reactive Protein, Plasminogen Activator Inhibitor- 1, and Fibrinogen with Oral Vitamin D Supplementation for Six Months in Patients with Type 2 Diabetes Mellitus

having Vitamin D Deficiency

Journal                      Lab

Physicians.2021.                                DOI https://doi.org/10.1055/s- 0041-1742285.

Yes

Serum adiponectin levels in patients with

rheumatoid arthritis.

Indian     J      Rheumatol.

2019; IP: 47.31.73.119.

Yes

A stuty of nontraditional biochemical markers and their relation to the level of fasting glycemia, in patients with type 2

diabetes mellitus.

Turk J Endocrinol Metab 2018;22:225-30.

Yes

Influence of age and gender on renal

function   by    using   egfr                in     healthy population.

ejbps, 2018, Volume 5,

Issue 7, 560-563.

Yes

Carbamylated                              hemoglobin                           can differentiate acute kidney injury from

chronic kidney disease.

Indian        J                 Nephrol 2018;28:187-90.

Yes

Protein carbonyls and protein thiols in

rheumatoid arthritis.

Int       J       Res       Med

Sci.2018:6(5);1738-41.

Yes

Serum Ferroxidase Activity of ceruloplasmin in Pulmonary Tuberculosis. J Clin Biomed Sci.

5(3):118-20.

J     Clin    Biomed      Sci. 5(3):118-20.

Yes

Implications of ischemia modified

albumin levels in hypertension.

Asian Pac J Trop Dis; 5

(Suppl 1): S190-1.

Yes

Ischemia-modified albumin in patients with hyperthyroidism and

hypothyroidism.

European     Journal                  of Internal               Medicine.               25;

e42-3.

Yes

Ischemia modified albumin and nitric oxide in hyperthyroidism.

J Invest Biochem. 1(1): 37-38.

Yes

Cobalt-albumin binding (CAB) assay: An advantageous and flaw free testing of albumin-cobalt binding.

Journal of Pharmaceutical and                      Biomedical Analysis.  2014;  99:79–

82.

Yes

Evaluation of protein oxidation and its association with lipid peroxidation and thyrotropin levels in overt and subclinical

hypothyroidism.

Endocrine.2012;                                DOI 10.1007/s12020-012-

9849-y.

Yes

8

Dr. M. Keerthi Tej Assistant Professor

Comparison     of     two                       methods     for measurement of serum chloride

JCSR.2022; 9:89-93

Yes

 

7

Dr. Y V Ramakrishna Reddy

Assistant Professor

Effect of Trimetazidine on Haemotological                                 Parameters                            in Experimental Animals with Coronary Heart Disease Alone and in Combination

with Diabetes Mellitus

Int of Clin Biochem and Res. 2022 ;29(1):17-21.

Yes

Epidemiological          Risk Factors Influencing the Formation of Renal Calculi, their Chemical Composition and

Association with Urinary Tract Infections.

Sch    Int    J          Biochem. 2020;3(12):260266.

Yes

YKL-40 as Inflammatory Marker in Reference to hs CRP in CKD Individuals with Uremic Toxicity to Diagnose the

Cardio Vascular Events.

Int J of Med and pharm Res 2023;4(3);720-25.

Yes

Uraemic Toxins and Endothelial Dysfunction in CKD and Hemodialysis individuals increasing the mortality

towards CVD.

Int J of Med and pharm Res 2023;4(3);953-57.

Yes

 

 

LIST OF ONGOING RESEARCH PROJECTS

 

Dr. Kondeti Madhavi Professor & HOD

Evaluation of clinico demographic profile, iodized salt usage, iodine status and thyroid profile in thyroid disorders of

Tirupati urbun population

On going as PI

 

Correlation of HOMA – IR with FBS and PP in obese and obese adolescence of

Nellore region

On going as PI

 

Study of glycemic status in T2DM patients treated with oral hypoglycemic

agents Vs Insulin

On going as PI

 

Awareness study of HPV in slum and non

slum urban level bodies of Nellore muncipal corporation

On going as PI

 

Study    of    aminoaciduria             in    Mental

retardation

On going as PI

 

Study of correlation of serum calcium and

magnesium with CRP in Covid 19

On going as Co-PI